Dr. T P Krishna Murthy

Assistant Professor

& Research Faculty

Department of Biotechnology

Ramaiah Institute of Technology

Bengaluru-560054

​

tpk@live.in

krishnamurthytp@msrit.edu

+91 80 2360 0822 Ext: 167

About

​I am a passionate teacher and researcher working as an assistant professor and research faculty at the Department of Biotechnology, Ramaiah Institute of Technology, Bengaluru. My research interests lie in the interface of biology & engineering and are aimed at developing solutions for green and sustainable solutions for better health and the environment. My research focused majorly on the development of various materials for the treatment of organic and inorganic pollutants from water and wastewater.  My research group also works on exploring medical plants, prebiotics and probiotics for the amelioration of various diseases. Recently I have initiated studies on understanding the practices of zero budget natural farming & organic farming and validating their potentials through scientific approaches.

2015–2021

PhD Chemical Engineering

Visvesvaraya Technological University

Belagavi-590018, Karnataka, INDIA

www.vtu.ac.in

2010-2012

M.Tech. Chemical Engineering

Manipal Institute of Technology

Manipal Academy of Higher Education

Manipal-576104, Karnataka, INDIA

www.manipal.edu

2005-2009

B.E. Biotechnology

Shridevi Institute of Engineering and Technology

(Affiliated to Visvesvaraya Technological University, Belagavi)

Tumakuru - 572 106, Karnataka, INDIA

www.shrideviengineering.org

August 2014-–Present

Assistant Professor

Department of Biotechnology

M S Ramaiah Institute of Technology

Bengaluru-560054, Karnataka, INDIA

www.msrit.edu

July 2012-June, 2014

Assistant Professor

Department of Biotechnology

Sapthagiri College of Engineering

Bengaluru-560057, Karnataka, INDIA

www.sapthagiri.edu.in

Lecturer 

Department of Biotechnology

Siddaganga Institute of Technology

Tumakuru572103, Karnataka, INDIA

Research Publications

1. Afraa Aqeel Zackria1, Bala Mohan Sivani1, Priyanka Venkatesh1, Ramya Pattabiraman1, S Birendra Kumar, Parasuraman P, T P Krishna Murthy. (2022) In silico screening of Natural compounds from Curcuma amada Roxb for inhibition of Helicobacter pylori: Molecular docking, dynamics and ADMET studies. International Journal of Pharmaceutical Research, 14 (1), 124-141. https://doi.org/10.31838/ijpr/2022.14.01.020 Scopus Indexed

2. Ankita Rao, T P Krishna Murthy, Vaishakh Nair. (2022). Remediation Analysis of an Azo and Anthraquinone Dye by Modified Low Sulphonated Lignin. Research Journal of Chemistry and Environment. 26 (3), 8-16. https://doi.org/10.25303/2603rjce0816 Scopus Indexed

3. Gouri Naira, Hema Sree G N S, Ganesan Rajalekshmi Saraswathy, V Marise Lakshmi Prasanna, T P Krishna Murthy. (2021) Application of comprehensive bioinformatics approaches to reconnoiter crucial genes and pathways underpinning Hepatocellular carcinoma – A drug repurposing endeavor. Medical Oncology, 38:145. Impact Factor: 3.064. https://doi.org/10.1007/s12032-021-01576-w

4. Nilofer Gerald Arakal, Vaishali Sharma, Avinash Kumar, Kavya B, Devadath N G, Birendra Kumar, Krishna Murthy T P, Manikanta Murahari. (2021) Ligand-based design approach of potential Bcl-2 inhibitors for cancer chemotherapy. Computer Methods and Programs in Biomedicine, 209 (September), 106347. Impact Factor: 5.428

5. ​

6. Sidharth Saxena, Sai Achyuth B, T P Krishna Murthy, Vivek Chandramohan, Arvind Kumar Yadav, Tiratha Raj Singh. (2021). Structural and functional analysis of disease-associated mutations in GOT1 gene: An in silico study. Computers in Biology and Medicine, 136 (September),104695. https://doi.org/10.1016/j.compbiomed.2021.104695  Impact Factor: 4.589

7. S Birendra Kumar, Swati Krishna, Sneha Pradeep, Divya Elsa Mathews, P Ramya, Manikanta Murahari, Krishna Murthy T P. (2021). Screening of Natural Compounds from Cyperus rotundus Linn against SARS-CoV-2 Main Protease: An Integrated Computational Approach. Computers in Biology and Medicine, 134 (July), 104524. https://doi.org/10.1016/j.compbiomed.2021.104524  Impact Factor: 4.589

8. Swati Krishna, S Birendra Kumar, Manikanta Murahari, Krishna Murthy T P (2021) Structure-based design approach of potential Bcl-2 inhibitors for cancer chemotherapy. Computers in Biology and Medicine, 134 (July), 104455. https://doi.org/10.1016/j.compbiomed.2021.104455  Impact Factor: 4.589

9. S Birendra Kumar, P Parasuraman, Krishna Murthy T P, Manikanta Murahari, Vivek Chandramohan. (2021). In silico screening of therapeutic potentials from Strychnos nux-vomica against the dimeric Main protease (Mpro) structure of SARS-CoV-2. Journal of Biomolecular Structure & Dynamics. Available online https://doi.org/10.1080/07391102.2021.1902394 Scopus and WOS Indexed

10. Divyashri G, Krishna Murthy T P, Subramaniam Sundareshan, Pavan Kamath, Manikanta Murahari, Saraswathy G R, Bindu Sadanandan. (2021). In silico approach towards the identification of potential inhibitors from Curcuma amada Roxb against H. pylori: ADME screening and molecular docking studies. BioImpacts, 11(2): 119-127. https://doi.org/10.34172/bi.2021.19  Impact Factor: 3.475

11. Bala Mohan Sivani, Priyanka Venkatesh, T P Krishna Murthy, S Birendra Kumar. (2021). In silco screening of antiviral compounds from Moringa oleifera for inhibition of SARS-CoV-2 Main Protease using computational approaches. Current Research in Green and Sustainable Chemistry. 4 (2021) 100202. https://doi.org/10.1016/j.crgsc.2021.100202 Scopus Indexed

12. Afraa Aqeel Zackria, Ramya Pattabiraman, T P Krishna Murthy, S Birendra Kumar, Blessy Baby Mathew, Vinai George Biju (2021) Computational Screening of Natural Compounds from Salvia plebeia R. Br. for Inhibition of SARS-CoV-2 Main Protease. Vegetos (Accepted). https://doi.org/10.1007/s42535-021-00304-z Scopus Indexed

13. T P Krishna Murthy, Trupthi Joshi, Shivani Gunnan, Nidhi Kulkarni, Priyanka V, S Birendra Kumar (2021) In silico Analysis of Phyllanthus amarus Phytochemicals as Potent Drugs Against SARS-CoV-2 Main Protease. Current Research in Green and Sustainable Chemistry, 4, 100159. https://doi.org/10.1016/j.crgsc.2021.100159 Scopus Indexed

14. Krishna Murthy T P, B S Gowrishankar, M N Chandraprabha, R Hari Krishna. Solution combustion synthesis of calcium aluminate nanocomposite using coffee husk extract as green fuel and its application in adsorptive amputation of anionic dyes. Materials Research Express 7 (2020): 035503. https://doi.org/10.1088/2053-1591/ab6b65  Impact Factor: 1.929

15. Krishna Murthy T P, B S Gowrishankar. Process optimization of methylene blue sequestration onto physically and chemically treated coffee husk-based adsorbent. SN Applied Sciences (2020): 2:836. https://doi.org/10.1007/s42452-020-2603-9  Scopus and WOS Indexed

16. Krishna Murthy T P, B S Gowrishankar, R Hari Krishna, Chandraprabha M N, Blessy B Mathew. Magnetic modification of hydrothermal treated coffee husk for adsorptive removal of methylene blue from synthetic wastewater: Kinetics, isotherms, and thermodynamic studies. Environmental Chemistry and Ecotoxicology, 2 (2020): 205-212. https://doi.org/10.1016/j.enceco.2020.10.002  Indexed in DOAJ

17. Krishna Murthy T P, R Hari Krishna, M N Chandraprabha, G Divyashri, Crasto Vanessa, S V Dhanyatha, S Megha and Patil Swarnima. (2020). Glycerol mediated solution combustion synthesis of nano magnesia and its application in the adsorptive removal of anionic dyes. Nano Express, 1, 030018. https://doi.org/10.1088/2632-959X/abc4d4 Indexed in Scopus and WOS

18. Krishna Murthy, T P., Gowrishankar, B. S., Krishna, R. H., Chandraprabha, M. N., & Rao, R. S. (2019). Influence of fuel nature on dye adsorption efficiency of solution combustion derived zinc oxide nanoparticles: A comparative study. Materials Research Express. 6 (5) 055512. https://doi.org/10.1088/2053-1591/aafe3f  Impact Factor: 1.929

19. Krishna Murthy, T. P., Gowrishankar, B. S., Prabha, M. C., Kruthi, M., & Krishna, R. H. (2019). Studies on batch adsorptive removal of malachite green from synthetic wastewater using acid treated coffee husk: Equilibrium, kinetics and thermodynamic studies. Microchemical Journal. 146 (May) 192-201. https://doi.org/10.1016/j.microc.2018.12.067  Impact Factor: 4.821

20. Bharath Y, Vivek C, T P Krishna Murthy, Bhavya S G, Gowrishankar B S, M Hanumanthappa. (2016). Prediction of deleterious single nucleotide polymorphisms and their effect on the sequence and structure of the human CCND1 gene. Journal of Taibah University Medical Sciences. 12(3), 221-228. https://doi.org/10.1016/j.jtumed.2016.07.009 Indexed in WOS and DOAJ

21. Bhavya S G, Manjunath D, Sharath R, Krishna Murthy T P, Gowrishankar B S. (2017). Reverse Micelles as a Bioseperation Tool for Enzymes. Journal of Proteins & Proteomics. 8 (2), 105-120. https://t.ly/yOgy

22. Krishna Murthy T P, Bhavya S G, Mamatha M, Blessy B Mathew, Manjunath Dammalli. (2015). Optimization of Microwave Assisted Extraction of Phenolic Compounds from Decalepis hamiltonii Root using Response Surface Methodology. International Research Journal of Pharmacy. 6 (11), 774-750. https://doi.org/10.7897/2230-8407.0611145

23. Vaishaly A.G, Blessy B. Mathew, N.B. Krishnamurthy, T.P. Krishna Murthy. (2015). Bioaccumulation of Heavy Metals by fungus. International Journal of Environmental Chemistry & Chromatography. 1(1), 15-21.

24. Krishna Murthy, T.P. and Manohar, B. (2014). Thermodynamic Modeling of Solubility of Mango Ginger Extract in Supercritical Carbon di Oxide Using Equation of State and Empirical Models. Journal of Food Science and Technology. 52 (9), 5557-5567. https://doi.org/10.1007/s13197-014-1667-1  Impact Factor: 1.946

25. Tenzin Tseten and Krishna Murthy T P. (2014). Advances and Biotechnological Applications in Biofuel Production. Open Journal of Renewable and Sustainable Energy. 1(2), 29-34. https://t.ly/s6Sq

26. Krishna Murthy, T.P. and Manohar, B. (2014). Mathematical Modeling of Supercritical Fluid Carbon Dioxide Extraction Kinetics of Bioactive Compounds from Mango Ginger. Open Journal of Organic Chemistry. 2(3), 36-40. https://t.ly/X7e0

27. Ajitha S, Krishna Murthy T P. (2014). α-Amylase Production and Applications: A Review. Journal of Applied & Environmental Microbiology. 2(4), 166-175. https://doi.org/10.12691/jaem-2-4-10

28. Sushma R, Dharini H, Sadiya Tabassum, Krishna Murthy T P, Bhavya S G, Manjunath D. (2014). Extraction of Polyphenols from Decalepis hamiltonii Root: Optimization of Batch Extraction Process Parameters. Research Journal of Pharmaceutical, Biological and Chemical Sciences. 5(4), 624-632. https://www.doi.org/10.7897/2230-8407.0611145

29. D. Chaithanya Devanad, Abishek D Jain, Sudipta S Bhattacherjee, P Liny, Krishna Murthy T P. (2014). Adsorption of fluoride from water using Spirulina Platensis and its measurement using fluoride Ion Selective Electrode. Research Journal of Chemical Sciences. 4(6),41-44. http://www.isca.in/rjcs/Archives/v4/i6/7.ISCA-RJCS-2014-71.php

30. Geetha P, Bhavana, Krishna Murthy T P, Ananda S, Krishna Murthy N B. (2014). Microwave Drying Kinetics of Germinated Horse Gram. Research Journal of Recent Sciences. 3(8), 96-102. http://www.isca.in/rjrs/archive/v3/i8/15.ISCA-RJRS-2014-780.php

31. Krishna Murthy T P, Harish A, Rashmi M and Blessy B Mathew. (2014). Effect of Blanching and Microwave Power on Drying Behavior of Green Peas (Pisum sativum). Research Journal of Engineering Sciences. 3(4), 10-18.

32. Monisha Jaishankar, Blessy Baby Mathew, Moshami Sailesh Shah, Krishna Murthy T.P., Sangeetha Gowda K.R. (2014). Biosorption of Few Heavy Metals Using Agricultural Wastes. Journal of Environment Pollution and Human Health, 2 (1), 1-6.

33. Harish A, Rashmi M, Krishna Murthy T P, Blessy B Mathew and Ananda S. (2014). Mathematical Modelling of Thin Layer Microwave Drying Kinetics of Elephant Foot Yam (Amorphophallus paeoniifolius). International Food Research Journal. 21 (3), 1045-1051.

34. A Harish, Vivek B S, Sushma R, Monisha J, T P Krishna Murthy. (2014). Effect of Microwave Power and Sample Thickness on Microwave Drying Kinetics of Elephant Foot Yam (Amorphophallus paeoniifolius). American Journal of Food Science and Technology. 2 (1), 28-35. http://www.sciepub.com/AJFST/abstract/1461

35. Krishna Murthy, T.P. and Manohar, B. (2014). Supercritical Carbon Dioxide Extraction of Phenolic Compounds from Mango Ginger Rhizhome (Curcuma amada Roxb.): Optimization of Process Parameters Using Response Surface Methodology. Biomedicine and Biotechnology. 2 (1), 14-19. http://pubs.sciepub.com/bb/2/1/3/index.html

36. Krishna Murthy T P. and Manohar, B. (2013). Grinding Studies of Mango Ginger: Mathematical Modeling of Particle Size Distribution and Energy Consumption. American Journal of Food Science and Technology, 1 (4), 70-76.

37.   Monisha J, Harisha A, Sushma R, Krishna Murthy T P, Blessy B Mathew, Ananda S. (2013). Biodiesel: A Review. International Journal of Engineering Research and Applications, 3 (6), 902-912. https://www.ijera.com/papers/Vol3_issue6/EV36902912.pdf

38. Blessy B Mathew, Danie Shajie, NehaWadwa, N B Krishna Murthy, T P Krishna Murthy and Rashmi M. (2013). Comparative Antioxidant Efficacy of Citrus Limonum Pulp and Peel - An In Vitro Study. Drug Invention Today, 5 (4), 296-301.

39. ​Blessy B Mathew and Krishna Murthy T P. (2013). Whey: From Waste to Worth. Global Research Analysis, 2 (8), 8-9. https://t.ly/HUmV

40. Shashidhar, G., Krishna Murthy, T. P., Giwari, G. K. and Manohar, B. (2013). Grinding of Coriander Seeds: Modeling of Particle Size Distribution and Energy Studies. Particulate Science and Technology, 35, 449-457. https://doi.org/10.1080/02726351.2013.772546  Impact Factor: 1.619

41. Krishna Murthy, T.P. and Manohar, B. (2013). Hot air drying characteristics of mango ginger: prediction of drying kinetics by mathematical modeling and artificial neural network. Journal of Food Science and Technology. 51 (12), 3712-3721. https://doi.org/10.1007/s13197-013-0941-y  Impact Factor: 1.946

42. Krishna Murthy, T.P. and Manohar, B. (2012). Microwave Drying of Mango ginger (Curcuma amada Roxb): Prediction of drying kinetics by mathematical modeling and artificial neural network. International Journal of Food Science and Technology, 47, 1229-1236. https://doi.org/10.1111/j.1365-2621.2012.02963.x Impact Factor: 2.773

​